Cellular and Biomolecular Laboratory

Christina Chan, Ph.D.

Research in our group focuses on understanding the mechanism of diseases such as diabetes, Alzheimer's disease and cancer, and identifying potential targets and pathways that may prevent or delay the onset of these diseases. We use systems biology and molecular biology approaches to achieve our goal. The former, systems biology, integrates and applies mathematics, statistics, engineering, physics, and computer science to understanding a range of complex biological regulatory systems. Concomitantly, we are developing delivery systems to target these pathways.

S. Patrick Walton, Ph.D.

Our group is focused on the analysis and application of nucleic acid-based technologies. Our goals are the understanding of critical biophysical and biochemical parameters involved in these processes and, in turn, the tuning of these parameters to achieve an improved technology. The current foci of the lab fall into two categories: i) mechanistic analysis of RNA interference (RNAi) and ii) parallel analytical platforms for cellular molecules.