Biography
Effective teaching, Curriculum development, Tendon mechanobiology, biomechanics, orthopaedics
Research Area
Awards
T. David Sisk Award for Best Original Research Paper, Sports Health Journal, 2011 “Infrapatellar Straps Decrease Patellar Tendon Strain at the Site of the Jumper’s Knee Lesion: A Computational Analysis Based on Radiographic Measurements”
New Investigator Recognition Awards Finalist, Orthopaedic Research Society, 2011 “In situ deflection of tendon cell cilia in response to tensile loading: An in vitro study.”
Cabaud Memorial Award, The American Orthopaedic Society for Sports Medicine, 2008 “Patellar tendon strain is increased at the site of the jumper’s knee lesion during knee flexion and tendon loading: Results and cadaveric testing of a computational model.”
Education
PhD Engineering Mechanics, Michigan State University, 2007
MS Biomedical Engineering, University of Michigan, 1998
MSE Mechanical Engineering, University of Michigan, 1998
BS Biomedical Engineering, Rensselaer Polytechnic Institute, 1996
Publications
Egerbacher M, Gardner K, Caballero O, Hlavaty J, Schlosser S, Arnoczky SP, Lavagnino M. Stress-deprivation induces an up-regulation of versican and connexin-43 mRNA and protein synthesis and increased ADAMTS-1 production in tendon cells in situ. Conn Tissue Res. 2021.
Yik S, Benjamin M, Lavagnino M, Morris D. DIAT (Depth-Infrared Image Annotation Transfer) for Training a Depth-Based Pig-Pose Detector. Proc. of Intelligent Robots and Systems (IROS), Oct. 2020. Finalist for Best Agri-Robotics Paper.
Mehdizadeh A, Gardiner BS, Lavagnino M, Smith DW. Effect of Collagen Length Distribution and Timing for Repair on the Active TGF-β Concentration in Tendon. Conn Tissue Res. 59(5):396-409, 2018.
Mehdizadeh A, Gardiner BS, Lavagnino M, Smith DW. Predicting tenocyte expression profiles and average molecular concentrations in Achilles tendon ECM from tissue strain and fiber damage. Biomech Model Mechanobiol. 16(4):1329-1348, 2017.
Lavagnino M, Brooks AE, Oslapas AN, Gardner KL, Arnoczky SP. Crimp Length Decreases in Lax Tendons due to Cytoskeletal Tension, but is Restored with Tensional Homeostasis. Muscles Ligaments Tendons J. 6(2):193-197, 2016.
Lavagnino M, Oslapas AN, Gardner KL, Arnoczky SP. Hypoxia Inhibits Primary Cilia Formation and Reduces Cell-Mediated Contraction in Stress-Deprived Rat Tail Tendon Fascicles Muscles Ligaments Tendons J. 6(2):193-197, 2016.
Rashmir-Raven AM, Lavagnino M, Sedlak A, Gardner KL, Arnoczky SP. Increased susceptibility of skin from HERDA (Hereditary Equine Regional Dermal Asthenia)-affected horses to bacterial collagenase degradation: a potential contributing factor to the clinical signs of HERDA. Vet Dermatol. 26(6):476-80, 2015.
Lavagnino M, Madison J, Williams MR, Arnoczky SP. The Equine Suspensory Ligament Exhibits a Heterogeneous Strain Pattern under Tensile Load. Vet Comp Orthop Traumatol. 28(5):306-11, 2015.
Lavagnino M, Gardner KL, Arnoczky SP. High magnitude, in vitro, biaxial, cyclic tensile strain induces actin depolymerization in tendon cells. Muscles Ligaments Tendons J. 5(2):124-128, 2015.
Lavagnino M, Malek K, Gardner KL, Arnoczky SP. Thermal energy enhances cell-mediated contraction of lax rat tail tendon fascicles following exercise. Muscles Ligaments Tendons J. 5(1):51-55, 2015.
Primary Department
