This project aims to develop the next generation of the next generation of brain-machine interfaces based on an emerging optogenetics technology. My research team has been working on design, fabrication, and characterization of a variety of implantable, power-efficient, hybrid optical/electrical microsystems, for optogenetic neuromodulation and electrical recording of functional brain activity with high spatiotemporal resolution.
Minimally Invasive Opto-ECoG Array
- Epidural optical stimulation via LEDs and simultaneous electrical recording via transparent microelectrodes
- Minimized photoelectrical artifacts without compromising optical throughput
- 32 channels with a channel size of 200 µm in diameter and a 500 µm separation
- Parylene-C as the flexible substrate and packaging material
Fully Implantable, Hybrid Optrode Arrays
- Tapered SU-8 waveguides with lengths varying from 300-1500 µm for delivering light to 3-dimentional neural networks
- A multi-layered cladding structure for electrical stimulation, extracellular recording, and reduction of photoelectrical artifacts,
Wirelessly Powered Optical Neuromodulators
- A switched-capacitor stimulation system for power-efficient wireless optogenetics: ≤3mW per channel
- Polymer-based system integration and packaging techniques
- Suitable for chronic implantation in small, freely behaving animals
Project Participants: Dr. Ki Yong Kown, Bin Fan, Wasif Afsari, Joshua I. Rosario Sepúlveda, Brenton Sirowatka, Zongheng Pu
Polycrystalline Diamond Based Neual Implants
- Neural probes capable of optical stimulation through LEDs and simultaneous recording through integrated microelectrodes
- Polycrystalline diamond head spreader for rapid dissipation of LED heat to surrounding biological environments
Project Participants: Bin Fan, Robert Rechenberg, Michael F. Becker