Neurochemical sensing with implantable microelectrodes has created multiple research opportunities in the field of neuroscience. The ability to record extracellular biopotentials and detect neurotransmitters with high sensitivity has enabled deeper understanding of brain and nervous system function. Diamond has many advantages over other electrode materials such as good biocompatibility, wide potential window, low double-layer capacitance, long-term stability, resistance to corrosion/fouling, and fabrication flexibility. In this work, we present a micromachined, implantable, all-diamond microfiber capable of reliable, precise neurochemical sensing. The all-diamond fiber consists of a conductive boron-doped polycrystalline diamond (BDD) core encapsulated in layers of insulating polycrystalline diamond (PCD) cladding.
