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About the Group

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Logo for Advanced MicroSystems and Circuits research group (AMSaC)

Mission and Direction

The Advanced MicroSystems and Circuits (AMSaC) group was formed at Michigan State University in 2001 by Dr. Andrew Mason. Since its founding, mission of this research group has been to develop innovative integrated circuit and microsystem approaches that enable a bridging between novel nano/micro-sensor technologies and high impact biomedical and environmental applications. While members of the AMSaC group typically develop expertise in solid-state devices, microelectronics, and microfabrication techniques, an inherent focus of the group is system-level integration of principles from multiple science/engineering/medicine disciplines across multiple design scales, from nano-technologies to software architectures, to address the challenges of autonomous wearable/implantable sensory microsystem. To that end, in recent years, we have greatly expanded our contributions in hardware efficient machine learning algorithms for embedded real-time signal processing of sensor and sensor array responses.

One area of major contribution for the AMSaC group is miniaturized electrochemical sensor arrays featuring nanostructured biological and chemical interfaces. From the development of electrochemical instrumentation circuits with a variety of high performance characteristics to pioneering lab-on-CMOS platforms for integration of sensor arrays with high density microfluidics, we continue to explore innovative approaches that enable electrochemical sensing techniques to resolve the growing demand for biological and chemical sensors in real-world applications.

Other areas of significant contribution include brain-machine-interface (BMI) and sensor technologies for biomedical research. Our work in the BMI field of has focused primarily on implantable neural recording and hardware-efficient spike sorting methods where we have pioneered approaches for massively high channel count recording arrays and recently directed efforts toward adaptive neurotechnologies. Our work in biosensor technologies has focused on development of instrumentation circuits and sensing platforms suitable to record the behavior of membrane protein arrays with many applications to biomedical research and new laboratory and clinical platforms to study and treat antibiotic resistance.

Research in the AMSaC group has historically focused on applications of human health and safety. While we continue this focus, we also strive to contribute to the environmental monitoring and related technologies that will help the world manage the impacts of climate change and adapt to a carbon-free future with energy-efficient smart sensor assistive devices.


Inherent to the multidisciplinary nature of work in the AMSaC group is the close affiliation with many other researchers and research groups. Our research partners and collaborators include:


The AMSaC group currently occupies ~1500 sq. ft. of laboratory space in MSU’s Engineering Building. Room 1522 is dedicated to microelectronics testing and system integration activities. Room 2203 is dedicated to design efforts and algorithm/software integration activities. We also share space in room 2150 with Dr. Li for microfabrication and chemical testing. Other microfabrication activities utilize the following cleanroom facilities:

For a complete list of equipment available in the AMSaC labs, click here.