3) Simulation of Image-Based Abdominal Aortic
of AAA growth and remodeling (G&R) provides an
opportunity to study changes in biomechanical parameters and the
evolution of wall mechanical properties (and shear stress if coupled
with hemodynamic simulation) during growth. As a step towards
patient-specific modeling of AAA, we have extended models of
stress-mediated vascular G&R to include image-based FE models
and simulated AAAs by inducing damage to elastin.
of damage shapes for elastin (left column) and consequent forms of
and stress distibutions after
column). The arrows indicate the regions of elevated stress
during AAA expansion.
S., Baek S., 2012, Medical image-based simulation of abdominal aortic
aneurysm growth. Mechanics Research Communications, in press
-Zeinali-Davarani S., Raguin L.G., Baek, S., 2011, An inverse
optimization approach toward testing different hypotheses of vascular
homeostasis using image-based models, International Journal of
Structural Changes in Solids, 3, 33-45
S., Raguin L. G., Vorp D.A. Baek S. 2011.
Identification of in vivo material and geometric parameters of a human
aorta: toward patient-specific modeling of abdominal aortic aneurysm.
Biomech Model Mechanobiol, 10, 689-699
- Zeinali-Davarani S., Sheidaei A., Baek S. 2011. A finite element
model of stress-mediated vascular adaptation: application to abdominal
aortic aneurysms. Comput Methods Biomech Biomed Eng, 9, 803-817
- Zeinali-Davarani S., Choi J., Baek S. 2009. On parameter estimation
biaxial mechanical behavior of arteries. J Biomech, 42,
Last update: Feb, 2012