CHEMS Seminar: Micro and Nano Technologies for Biomedical Applications

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Event Date/Time: 
October 11, 2012 - 9:10am to 10:30am
Event Location: 
2250 Engineering Building
Speaker: 
Dr. Murty Vyakarnam
CHEMS Seminar

Abstract

 
 

The advances taking place in nanotechnologies and MEMS have provided many opportunities in the bio-medical field ranging from micro/nano scaffolds for regenerative medicine; MEMS based smart miniaturized devices; nanoparticles for tissue targeting/drug delivery; microfluidic chips for diagnostics; nanocomposites for orthopedic implants; to implantable devices with micro/nano surfaces that enhance tissue fixation and/or host response. Drawing inspiration from nature we created unique micro & nano scale biomimetic surfaces and multi-layered structures from biomaterials that were both bio-degradable as well as bio-durable. These topographical features provide physical and biological responses that can be tailored for different device applications, often without chemical modifications of surfaces which would have added complexity in the regulatory pathways. Results from tissue fixation, modulation of protein binding for diagnostic chips, and controlling drug release from micro-well chips will be presented. Challenges in process scale-up and the development of micro/nano imprinting as a scalable and cost effective technology will be presented.

 

 
 
Bio
 
 
Dr. Murty Vyakarnam is Director R&D at Advanced Technologies and Regenerative Medicine (ATRM), LLC - a R&D organization within Global Surgery Group of Johnson & Johnson. He has been with Johnson & Johnsons for over 16 years working in the field of medical devices primarily in the cardio/neuro vascular, orthopedic, wound healing/repair, and regenerative medicine areas from concept research, product development, clinical trials to product launches. His group focuses on process and device development encompassing a variety of technologies: nanotechnologies, MEMs, tissue/ organ engineering scaffolds, drug-device combination technologies, and biodegradable polymer processing. He also leads the MD&D Nanotechnology Workstream and drives cross company collaborations in nanotechnologies. Dr. Vyakarnam received his B.Tech from Andhra University (Visakhapatnam, India), M.S. and Ph.D. from Michigan State University (East Lansing, MI) all in Chemical Engineering. He received numerous awards including SAMPE’s best graduate student research in 1996 and Johnson & Johnson’s Philip B. Hofmann award for his outstanding scientific achievement in 2002. He is an inventor on over 35 issued and/or published US patents and co-authored several publications including 2 book chapters.