Syed A. Hashsham, Ph.D.
Civil and Environmental Engineering
A126 Engineering Research Complex
East Lansing, MI 48824
Phone: (517) 355-8241
Fax: (517) 355-0250
Web (Lab): http://www.egr.msu.edu/~hashsham/
- Biological Principles of Environmental Engineering
- Microbiology for Environmental Health Engineering
- Feasibility Studies in Environmental Engineering
- Introduction to Environmental Engineering
- On-chip PCR
- Flexible Biochip for Highly Parallel Microbial Detection
- GeneScreen: A low-cost and high-density DNA biochip for detecting
up to 30,000 microorganisms
- Development of microarrays for evaluating phylogenetic and functional
diversity of the microbial world
- Bioinformatics Pilot Program for the Assessment of Virulence-Factor
and Activity relationships (VFARs) for Waterborne Disease Microorganisms
- Emerging microbial indicator technologies
- Landfill Bioreactors: Field Scale Evaluation
- Sustainable Manure Management in Dairy Industry by Struvite Recovery
Dr. Hashsham’s research focuses on environmental molecular biology
and mathematical tools to address environmental engineering issues.
Current research focuses on the development of DNA biochips for parallel
detection of microorganisms important to drinking water and wastewater.
Approaches for improved detection limit, sample concentration, probe
design, and validation are of special interest. Dr. Hashsham is also
interested in developing new tools to manage mixed microbial communities
and bioreactor landfills.
University of Illinois at Urbana-Champaign: Ph.D., Environmental Engineering
- Lukas M. Wick, Jean Marie Rouillard, Thomas S. Whittam, Erdogan
Gulari, James M. Tiedge and Syed A. Hashsham, On-chip non-equilibrium
dissociation curves and dissociation rate constants as methods to
assess specificity of oligonucleotide probes, Nucleic Acids
Research, 34(3):e26; doi: 10.1093/nar/gnj024, 2006.
- Duran, M., Alm, E. W., Stedtfeld, R. D., Haznedaroglu, B. Z., and
Hashsham, S. A., Detection and Occurrence of Indicator Organisms
and Pathogens, Water Environment Research, Vol. 77, No.
6, pp. 659-717, 2005.
- Hashsham, S.A., Wick, L.M., Rouillard, J-M., Gulari, E., and J.M.
Tiedge, Potential of DNA microarrays for developing parallel detection
tools (PDTs) for microorganisms relevant to biodefense and related
research needs, Biosensors and Bioelectronics, Volume 20,
Issue 4, Pages 668-683, 2004.
- Denef, V.J., J. Park, J.L. Rodrigues, T.V. Tsoi, S.A. Hashsham and
J.M. Tiedje, Validation of a more sensitive method for using spotted
oligonucleotide DNA microarrays for functional genomics studies on
bacterial communities, Environmental Microbiology, 5(10),
- Sun, B., B.M. Griffin, R.K. Kehrer, S.A. Hashsham, and J.M. Tiedge,
Microbial reductive dechlorination of 1.1.1-trichloroethane to
chloroethane, Science, 298: 1023, 2002.
- Dollhopf, S.L., S.A. Hashsham, and J.M. Tiedge, Interpreting
16S rDNA T-RFLP Data: Application of self-organizing maps and principal
component analysis to describe community dynamics and convergence,
Microbial Ecology, 42 (4): 495-505, 2001.
- Hashsham, S., A. Fernandez, S. Dollhopf, F. Dazzo, R. Hickey, J.
Tiedje, and C. Criddle, Parallel processing of substrate correlates
with greater functional stability in methanogenic bioreactor communities
perturbed by glucose, Applied and Environmental Microbiology,
66 (9): 4050-4057, 2000.